What is the myDNAge® Test?
The myDNAge® Test is an epigenetic age determination test. This biological age test is based on Dr. Horvath’s epigenetic aging clock and utilizes our proprietary SWARM™ (Simplified Whole-panel Amplification Reaction Method) technology to analyze DNA methylation patterns of over 2,000 loci on the human genome and generate epigenetic age predictions in a high throughput manner.
What is Epigenetics?
Epigenetics refers to the modification on our DNA, RNA, or protein, which can change/regulate these molecules without altering the primary sequence. Our genetics, lifestyle, the food we eat, and the environment we live in, affects these modifications, and therefore affects how our genes behave.
Why is this important? Epigenetic mechanisms play a crucial role in regulating biological processes as diverse as development, learning, metabolism, and in the progression of diseases such as cancer.
DNA methylation, the most abundant and best-studied epigenetic modification, is now recognized as a reliable indicator of biological age. The myDNAge® Epigenetic Aging Clock service is based on Dr. Steve Horvath’s aging clock, the gold standard of epigenetic age calculator built using DNA methylation data.
Epigenetics and You
Some food keeps us healthy while others cause us harm. Acute or chronic stress could impact our long-term health. When we get older, age-related disease will come and haunt us.
DNA is our blueprint that makes us who we are. However, it cannot be denied that our life choices can also influence how we grow and develop. The field of epigenetics is growing rapidly and learning how our diet, lifestyle, and environment could affect our growth and development would revolutionize how we select our life choices.
Epigenetics can explain how these external factors cause the modifications on our DNA and its structures, which results in gene regulation.
What is the Epigenetic Aging Clock?
Epigenetic modifications refer to heritable changes in the genome that occur independently of changes to the primary DNA sequence. Epigenetics plays crucial biological roles in processes as diverse as development, learning, metabolism, and in the progression of diseases such as cancer. DNA methylation, the most abundant and best studied epigenetic modification, is now recognized as a reliable indicator of biological age1-5. Dr. Steve Horvath’s epigenetic aging clock, the gold standard of DNA Age Test or Biological Age Test, was built using data generated from thousands of samples. His analytical method has been cited in over 600 peer reviewed scientific publications. The myDNAge® Epigenetic Aging Clock service is based on Steve Horvath’s aging clock and utilizes SWARM™ (Simplified Whole-panel Amplification Reaction Method) technology to analyze DNA methylation patterns of >2000 genetic loci and provide epigenetic age predictions in a high throughput manner.
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